Cy3-UTP 抑制剂 BMPO Leukotriene D4 荧光染料 DMAPP 定制合成
Tricine中文别名:N-2-羟乙基哌嗪-N’-3-丙磺酸 | 4-(2-羟乙基)-1-哌嗪丙磺酸(HEPPS) | 3-[4-(羟乙基)-1-哌嗪基]丙磺酸 | 4-(2-羟乙基)-1-哌嗪丙磺酸
1、4-(2-羟乙基)-1-哌嗪丙磺酸用途:
EPPS is a rescuer of A? aggregation and behavioural deficits, binding to A? aggregates and converting them into monomers.
2、4-(2-羟乙基)-1-哌嗪丙磺酸物理化学性质:
分子性质数据:
1、 摩尔折射率:61.32
2、 摩尔体积(m3/mol):196.2
3、 等张比容(90.2K):527.2
4、 表面张力(dyne/cm):52.0
5、 极化率(10 -24cm 3):24.31
1.疏水参数计算参考值(XlogP):-3.6
2.氢键供体数量:2
3.氢键受体数量:6
4.可旋转化学键数量:6
5.互变异构体数量:无
6.拓扑分子极性表面积89.5
7.重原子数量:16
8.表面电荷:0
9.复杂度:280
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1
3、4-(2-羟乙基)-1-哌嗪丙磺酸文献:
Comparison of MDCK-MDR1 and Caco-2 cell based permeability assays for anti-malarial drug screening and drug investigations. J. Pharmacol. Toxicol. Methods 70(2) , 188-94, (2014)
Heat Shock Protein 90 Associates with the Per-Arnt-Sim Domain of Heme-free Soluble Guanylate Cyclase: IMplications for Enzyme Maturation. J. Biol. Chem. 290 , 21615-28, (2015)
EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nat. Commun. 6 , 8997, (2015)
4、4-(2-羟乙基)-1-哌嗪丙磺酸英文别名:
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