PE 154

PE 154 (订货以CAS编码或英文名称为准)

人乙酰胆碱酯酶(AChE)和丁酰胆碱酯酶(BChE)抑制剂,PE 154 are known to associate with β-amyloid plaques, and histological co-localization of AChE and Ab peptides is well established in Alzheimer’s disease.
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编号:MED17155
CAS号:1192750-33-6
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中文名称: PE 154
中文别名: PE 154
英文名称: PE 154
英文别名: PE 154;2-(1,2,3,4-Tetrahydro-9-acridinyl)hydrazide-4-[[[7-(diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid
CAS号: 1192750-33-6
人乙酰胆碱酯酶(AChE)和丁酰胆碱酯酶(BChE)抑制剂,PE 154 are known to associate with β-amyloid plaques, and histological co-localization of AChE and Ab peptides is well established in Alzheimer’s disease. PE-154 is a fluorescent inhibitor of both AChE and BChE with IC50 values of 280 pM and 16 nM. PE-154 stains Aβ plaques in both rodent and human tissue samples, and does not cross react with phospho-tau.
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